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GSK Commits $800M to Expand Pennsylvania Manufacturing Facility

The expansion project will include the demolition of existing buildings.

GSK corporate headquarters building with orange logo sign against blue sky and clouds
Wirestock/iStock

Pennsylvania Governor Josh Shapiro said his state has secured an over $800 million investment from global biopharma company GSK to expand its operations in Montgomery County. The expansion will create more than 300 new jobs over the next five years and retain approximately 4,500 existing full-time jobs across the state.

GSK is expanding its facilities in Upper Merion Township, with construction planned to begin in 2027. The expansion will establish a biopharmaceutical innovation and manufacturing hub, integrating commercial production, research and development, and advanced digital capabilities in a single site. This announcement marks GSK’s second major expansion in Pennsylvania since the Shapiro took office, previously investing $800 million in Lancaster County.

“GSK’s decision to make another major investment in Pennsylvania is a strong signal that we have the innovation ecosystem, talent, and infrastructure to support the next generation of biopharmaceutical manufacturing,” said Department of Community and Economic Development (DCED) Secretary Rick Siger in a statement. “This project will create hundreds of new jobs, strengthen the economy, and build on GSK’s longstanding commitment to Pennsylvania. The Shapiro Administration will continue to support and invest in companies that further boost our economy and provide real opportunity for Pennsylvanians.”

The expansion project will include the demolition of existing buildings and construction of new and enhanced facilities including a commercial-scale biologics manufacturing facility capable of supporting both clinical and commercial supply, a co-located research and development pilot plant to accelerate tech transfer and process development, and a centralized quality control lab and manufacturing science & technology (MSAT) hub.

“Investing in additional commercial and R&D manufacturing with advanced digital capabilities at our Upper Merion site will help accelerate the development and supply of future medicines for patients,” said Regis Simard, President, GSK Global Supply Chain, in a statement. “The Commonwealth of Pennsylvania has been an important partner in supporting GSK's growth, innovation, and manufacturing footprint in the United States. By expanding in Upper Merion, we're building on that longstanding partnership while creating high-quality jobs and strengthening our ability to deliver the next generation of medicines.”

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